Management of asthma in children with long QT syndrome.

The Long QT syndrome (LQTS) is a rare disorder in which patients are prone to life threatening ventricular arrhythmia and is a leading cause of sudden death in childhood. Asthma is common and its management in those with LQTS presents a number of potential difficulties. The mainstay of therapy in LQTS is beta-blockade, which may worsen symptoms of asthma. Conversely, beta-agonist therapy is the mainstay of asthma management; which, in those with LQTS, may provoke ventricular arrhythmias. We review available data regarding the management of coexistent LQTS and asthma, and provide a summary of the necessary considerations in managing these patients. Crown Copyright © 2011. Published by Elsevier Ltd. All rights reserved.

Citation

Samuel Collins, John Widger, Andrew Davis, John Massie. Management of asthma in children with long QT syndrome. Paediatric respiratory reviews. 2012 Jun;13(2):100-5

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PMID: 22475256

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