A M Lazar, N D Straja, E Brătucu
Clinic of Surgery I, Bucharest Oncology Institute "Al. Trestioreanu", University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania. angelalazar.2008@yahoo.com
Chirurgia (Bucharest, Romania : 1990) 2012 Jan-FebRetroperitoneal sarcomas are rare tumors associated with a high rate of recurrence and very bad prognosis. Their only efficient treatment is a negative- margin surgical resection that is extremely difficult to achieve. Retroperitoneal metastases from extremity sarcomas are considered unusual. In literature, such a metastatic pattern is described extremely rarely. In this paper we report a case of a very aggressive extremity chondrosarcoma, associated with local recurrence, multiple distant metastases, that finally led to a retroperitoneal metastasis. The recurrence and progression of the sarcoma in this localization were impressive, with a fast overcome of therapeutic options. Chemo- and radiotherapy have not proved to be efficacious in this context and they could have had a role in the deterioration of patient state of health. New tumor markers for the detection and follow-up of these tumors should be considered.
A M Lazar, N D Straja, E Brătucu. An unusual sarcomatous retroperitoneal metastasis. A rare case report with a brief literature review. Chirurgia (Bucharest, Romania : 1990). 2012 Jan-Feb;107(1):108-14
PMID: 22480125
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