Glioblastoma following radiosurgery for meningioma.

We report a patient who underwent gamma knife radiosurgery to treat recurrent meningioma after microsurgery and thereafter developed secondary malignancy adjacent to the original tumor. A 47-year-old woman had underwent resection of the olfactory groove meningioma. Then radiosurgery was done three times over 4 year period for the recurrent tumor. After 58 months from the initial radiosurgery, she presented with headache and progressive mental dullness. Huge tumor in bifrontal location was revealed in MRI. Subsequent operation and pathological examination confirmed diagnosis of glioblastoma. This case fits the criteria of radiation-induced tumor and the clinical implication of the issue is discussed.

Citation

Hyun Seok Lee, Jong Hyun Kim, Jung-Il Lee. Glioblastoma following radiosurgery for meningioma. Journal of Korean Neurosurgical Society. 2012 Feb;51(2):98-101

PMID: 22500202

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