Membrane fission: curvature-sensitive proteins cut it both ways.

Boucrot et al. (2012) demonstrate a membrane fission mechanism independent of nucleotide hydrolysis that is based on membrane insertion of amphipathic helices. They show that, for N-BAR domain proteins, which promote membrane curvature but also contain amphipathic helices, fission is opposed by the BAR domain that stabilizes tubular membrane structures. Copyright © 2012 Elsevier Inc. All rights reserved.

Citation

Andrew Callan-Jones, Patricia Bassereau. Membrane fission: curvature-sensitive proteins cut it both ways. Developmental cell. 2012 Apr 17;22(4):691-2

PMID: 22516194

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