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To review the evidence that isoflavones are effective treatments for menopausal symptoms and to present the safety data. The databases Scopus, ScienceDirect and Primo Central Index were searched and preference was given to systematic reviews and meta-analyses. The available evidence suggests that isoflavones do not relieve menopausal vasomotor symptoms any better than placebo. Long-term safety studies suggest that women who consume a diet high in isoflavones may have a lower risk of endometrial and ovarian cancer. Isoflavones cannot be recommended for the relief of hot flushes. Crown Copyright © 2012. Published by Elsevier Ireland Ltd. All rights reserved.

Citation

John A Eden. Phytoestrogens for menopausal symptoms: a review. Maturitas. 2012 Jun;72(2):157-9


PMID: 22516278

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