Nasopharyngeal lactate dehydrogenase concentrations predict bronchiolitis severity in a prospective multicenter emergency department study.

We reexamined the finding of an inverse relationship between values of nasopharyngeal lactate dehydrogenase, a marker of the innate immune response, and bronchiolitis severity. In a prospective, multicenter study of 258 children, we found in a multivariable model that higher nasopharyngeal lactate dehydrogenase values in young children with bronchiolitis were independently associated with a decreased risk of hospitalization.

Citation

Jonathan M Mansbach, Pedro A Piedra, Federico R Laham, Alexander J McAdam, Sunday Clark, Ashley F Sullivan, Carlos A Camargo. Nasopharyngeal lactate dehydrogenase concentrations predict bronchiolitis severity in a prospective multicenter emergency department study. The Pediatric infectious disease journal. 2012 Jul;31(7):767-9

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PMID: 22517336

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