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Neuroblastoma (NBL), a malignant embryonic tumor derived from neural crest cells, is the most common tumor worldwide among children less than 1 year of age. Metastasis to the mandible is uncommon. This article reports the case of a 15-month-old male diagnosed with NBL with bone metastasis including the mandible which resulted in severe tooth mobility. Dentists or pediatricians should consider the primary or metastatic tumors of the maxillofacial region in the differential diagnosis in children presenting with premature loss of teeth related to tooth mobility.


Esma Kürklü, Halil Haldun Emiroğlu, Rejin Kebudi, Didem Oner Ozdaş, Inci Ayan, Omer Görgün, Bülent Zülfikar, Ensar Yekeler, A K Gülsüm. Metastatic mandibular neuroblastoma: a rare cause of tooth mobility. The Journal of clinical pediatric dentistry. 2011;36(2):203-6

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PMID: 22524085

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