Radiation pneumonitis following yttrium-90 radioembolization: case report and literature review.

Chadwick L Wright, Jeff D Werner, Jerry M Tran, Vanessa L Gates, Ali A Rikabi, Manisha H Shah, Riad Salem

Department of Radiology, Ohio State University, Columbus, Ohio, USA.

Journal of vascular and interventional radiology : JVIR 2012 May

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Radiation-induced pneumonitis (RP) is a rare complication of radioembolization with yttrium-90 ((90)Y) microspheres. The present report describes a case of RP in a patient with liver metastases from a gastrointestinal stromal tumor after radioembolization with (90)Y glass microspheres. This patient developed clinical, functional, and radiographic findings consistent with RP, with near-complete pulmonary parenchymal recovery and no clinical evidence of relapse or progressive decline in pulmonary function over a 9-month period. As clinical use of radioembolization expands, rare adverse events such as RP may become more frequent. It is essential that interventional radiologists, radiation/medical oncologists, and nuclear medicine physicians recognize this potential complication. Copyright © 2012 SIR. Published by Elsevier Inc. All rights reserved.

Citation

Chadwick L Wright, Jeff D Werner, Jerry M Tran, Vanessa L Gates, Ali A Rikabi, Manisha H Shah, Riad Salem. Radiation pneumonitis following yttrium-90 radioembolization: case report and literature review. Journal of vascular and interventional radiology : JVIR. 2012 May;23(5):669-74