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This report describes a transient hypertrophic cardiomyopathy with right-ventricle outlet tract obstruction (RVOTO) induced by perinatal stress due to a major surgical procedure in a female newborn with congenital abnormalities. On day 10, she presented with heart failure, abnormal B-type natriuretic peptide (BNP), and an echocardiogram showing normal wall thickness. An in-hospital follow-up echocardiogram showed biventricular hypertrophy and RVOTO. At discharge, the infant was asymptomatic, with a normal echocardiogram and BNP. Transient RVOTO triggered by surgical stress and abnormal BNP have not been reported previously. Pathophysiology, the role of BNP, and clinical characteristics are discussed.

Citation

Jesus Yañez, David Rodriguez, Cristina Treviño, Adriana Valdez, Carlos Jerjes-Sanchez. Stress transient hypertrophic cardiomyopathy and B-type natriuretic peptide role. Pediatric cardiology. 2013 Mar;34(3):702-6

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PMID: 22526216

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