Stanisław Niemczyk, Katarzyna Romejko-Ciepielewska, Longin Niemczyk
Department of Internal Diseases, Nephrology and Dialysis, Military Institute of Health Services, ul. Szaserow 128, 04-141 Warsaw, Poland. sniemczyk@wim.mil.pl
Endokrynologia Polska 2012The authors discussed disorders in adipocytokines' function in chronic renal failure (CRF) and their clinical implications. Adipocytokines' concentrations in CRF are in most cases elevated, which is associated with decreased level of their excretion. This may cause number of clinical implications such as inflammation, loss of appetite, development of protein energy wasting (PEW) syndrome and the progress of artherosclerosis, what leads to increased mortality in a group of patients with end-stage renal disease (ESRD). Disturbances in sexual hormones function are also characteristic for CRF. Disorders in fertility, sexual life and decreased quality of life are observed in patients with CRF. Therapeutic procedure is complicated and not fully effective.
Stanisław Niemczyk, Katarzyna Romejko-Ciepielewska, Longin Niemczyk. Adipocytokines and sex hormone disorders in patients with chronic renal failure (CRF). Endokrynologia Polska. 2012;63(2):148-55
PMID: 22538755
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