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Clostridium sordellii is a Gram-positive bacterium which can cause a serious toxic shock syndrome with a mortality of up to 69%. C. sordellii is a part of the normal vaginal flora in up to 10% of all women. This case describes a fatal case of a healthy 49 year-old woman with a C. sordellii-infection originating from an ovarian cyst. Quick diagnosis is difficult because of the non-specific flu-like symptoms. Survival requires immediate source control and specific antibiotic therapy capable of suppressing toxin production. In rodents superantigen antibodies have shown neutralizing effects.

Citation

Jens Holst Bjerregaard, Charlotte Bülow, Laura Katrine Buskov, Jon Gitz Holler. Fatal Clostridium sordellii infection originated in an ovarian cyst]. Ugeskrift for laeger. 2012 Apr 30;174(18):1231-2

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PMID: 22546161

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