Cleidbrevoids A-C, new clerodane diterpenoids from Cleidion brevipetiolatum.

Yuan-Yuan Cheng, Shi-Fei Li, Yu Zhang, Gui-Hua Tang, Ying-Tong Di, Xiao-Jiang Hao, Shun-Lin Li, Hong-Ping He

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People's Republic of China.

Fitoterapia 2012 Sep

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Three new clerodane-type diterpenoids with a rare sulfoxide group, cleidbrevoids A-C (1-3), were isolated from the twigs and leaves of Cleidion brevipetiolatum. Their structures were elucidated on the basis of spectroscopic methods and the absolute configuration of compounds 1 and 3 was determined by X-ray analysis. Compound 3 showed weak inhibitory against HIV-1. Copyright © 2012 Elsevier B.V. All rights reserved.

Citation

Yuan-Yuan Cheng, Shi-Fei Li, Yu Zhang, Gui-Hua Tang, Ying-Tong Di, Xiao-Jiang Hao, Shun-Lin Li, Hong-Ping He. Cleidbrevoids A-C, new clerodane diterpenoids from Cleidion brevipetiolatum. Fitoterapia. 2012 Sep;83(6):1100-4