Mohan-Kumari H Puttananjaiah, Mohan A Dhale
Department of Food Microbiology, Central Food Technological Research Institute, Council of Scientific and Industrial Research, Mysore, India. dhalem@nio.org
Journal of basic microbiology 2013 JanCarbon catabolite repression is generally considered as a regulatory mechanism to ensure sequential synthesis of secondary metabolites. In this study we made an attempt to understand the influence of amylase activity on pigment synthesis in Penicillium sp NIOM-02. The amylase activity is inversely proportional to pigment production. The high performance liquid chromatography analysis of amylase reaction revealed glucose as the major product of starch hydrolysis. The fungus grown in acarbose (inhibitor of amylase) incorporated media produced higher quantities of pigments. Apparently, glucose released due to amylase activity influenced the pigment synthesis by cAMP signaling pathway. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Mohan-Kumari H Puttananjaiah, Mohan A Dhale. Glucose released by hydrolytic activity of amylase influences the pigment synthesis in Penicillium sp NIOM-02. Journal of basic microbiology. 2013 Jan;53(1):93-7
PMID: 22581402
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