Reversible cerebral vasoconstriction syndrome induced by adrenaline.

Jose-Alberto Palma, Ariadna Fontes-Villalba, Pablo Irimia, Reyes Garcia-Eulate, Eduardo Martinez-Vila

University Clinic of Navarra, Pamplona, Spain.

Cephalalgia : an international journal of headache 2012 Apr

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Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by acute severe thunderclap headaches and evidence of multifocal, segmental, reversible vasoconstrictions of the cerebral arteries. Several precipitating factors have been identified and reported, including the use of recreational substances or sympathomimetic drugs and the postpartum state. Here we present the case of a woman who developed RCVS after the administration of adrenaline (epinephrine) in the setting of an anaphylactic reaction during antibiotic allergy testing. To our knowledge, this is the first reported case of RCVS following the administration of exogenous adrenaline. This case contributes to the understanding of the physiopathological mechanisms underlying reversible cerebral vasoconstriction.

Citation

Jose-Alberto Palma, Ariadna Fontes-Villalba, Pablo Irimia, Reyes Garcia-Eulate, Eduardo Martinez-Vila. Reversible cerebral vasoconstriction syndrome induced by adrenaline. Cephalalgia : an international journal of headache. 2012 Apr;32(6):500-4