Protein-losing enteropathy and premature ovarian failure in a young woman with systemic lupus erythematosus.

Y S Chang, C C Lai, W S Chen, S H Wang, C T Chou, C Y Tsai

Division of Allergy, Immunology and Rheumatology and, Department of Medicine, Taipei Medical University Shuang Ho Hospital, Taipei, Taiwan.

Lupus 2012 Oct

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Protein-losing enteropathy (PLE) and autoimmune oophoritis are unusual manifestations of systemic lupus erythematosus (SLE). Autoimmune oophoritis may result in menstrual disturbance and spontaneous premature ovarian failure. However, there is no validated examination to confirm the diagnosis and it is easily neglected in patients with ovarian insufficiency. A 31-year-old woman with SLE presented with PLE and autoimmune oophoritis during the long course of flares and remissions in her lupus activity. The synchronism implied the association between the two. Moreover, both conditions simultaneously had a good response to cyclosporine A (CsA) therapy.

Citation

Y S Chang, C C Lai, W S Chen, S H Wang, C T Chou, C Y Tsai. Protein-losing enteropathy and premature ovarian failure in a young woman with systemic lupus erythematosus. Lupus. 2012 Oct;21(11):1237-9