Occurrence of cerebrocortical necrosis in a goat in Okinawa prefecture, Japan.

Masanao Matayoshi, Osamu Tsuha, Shusaku Shimoji, Miho Araki, Tsutomu Uchihara, Tomotaka Arakaki, Tomomi Ozawa

Okinawa Prefecture Central Livestock Hygiene Service Center, 2505 Oozato, Oozato, Nanjyo, Okinawa 901-1202, Japan. matayoma@pref.okinawa.lg.jp

The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2012 Sep

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A 6-month-old male Nubian goat suddenly showed dullness, tachypnea, recumbency and opisthotonus in August 2011 in Okinawa, Japan. The goat was consequently necropsied: gross lesions in the brain included slightly swollen foci of yellowish discoloration on the cerebral hemisphere. Histopathologically, necrosis of the cortex with ischemic changes of neuronal cells was present, and swelling of the vascular endothelium, thickening of the basement membrane and diffuse infiltration of macrophages were observed in the cerebral lesion. Autofluorescence of the cerebral cortex was confirmed by an ultraviolet light test. The thiamine levels of the blood serum and tissue samples (brain, liver and heart) of the goat were low compared with goats from the same herd. The goat was diagnosed with cerebrocortical necrosis (CCN). This is the first case report of caprine CCN in Japan.

Citation

Masanao Matayoshi, Osamu Tsuha, Shusaku Shimoji, Miho Araki, Tsutomu Uchihara, Tomotaka Arakaki, Tomomi Ozawa. Occurrence of cerebrocortical necrosis in a goat in Okinawa prefecture, Japan. The Journal of veterinary medical science / the Japanese Society of Veterinary Science. 2012 Sep;74(9):1199-201