Pentoxifylline use in dermatology.

Seray Külcü Çakmak, Atil Çakmak, Müzeyyen Gönül, Arzu Kiliç, Ülker Gül

Ankara Numune Education and Research Hospital Dermatology Clinic, 701. sok 18/8 Yildiz Çankaya, Ankara, Turkey. seraycakmak@yahoo.com

Inflammation & allergy drug targets 2012 Dec

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Pentoxifylline is methylxanthine derivative which is used in microcirculatory disorders as a vasoactive drug. Novel immunomodulatory properties of pentoxifylline have been reported including the down regulation of tumour necrosis factor-α synthesis and other inflammatory cytokines. Studies have shown that pentoxifylline might be efficacious in a wide spectrum of skin diseases. This article focuses on the use of pentoxifylline which is a safe and cheap drug in various dermatological disorders.

Citation

Seray Külcü Çakmak, Atil Çakmak, Müzeyyen Gönül, Arzu Kiliç, Ülker Gül. Pentoxifylline use in dermatology. Inflammation & allergy drug targets. 2012 Dec;11(6):422-32