Correlation Engine 2.0
Clear Search sequence regions

Insulin-like growth factors (IGFs) play an integral role in development, growth, and survival. This article details the current understanding of the effects of IGFs in the peripheral nervous system (PNS) during health and disease, and introduces how the IGF system regulates PNS development and impacts growth and survival of PNS cells. Also discussed are implications of IGF signaling in neurodegeneration and the status and prospects of IGF therapies for PNS conditions. There is substantial support for the application of IGF therapies in the treatment of PNS injury and disease. Copyright © 2012 Elsevier Inc. All rights reserved.


Stacey A Sakowski, Eva L Feldman. Insulin-like growth factors in the peripheral nervous system. Endocrinology and metabolism clinics of North America. 2012 Jun;41(2):375-93, vii

Expand section icon Mesh Tags

Expand section icon Substances

PMID: 22682636

View Full Text