The recent discovery of a new class of RNA in a centrosome may be an indirect evidence of the centrosomal hypothesis of cellular ageing and differentiation. The presence of a reverse transcriptase domain in this class of RNA, together with its specificity to this organelle, makes the centrosome a place of information memorizing and reproduction. This feature of centrosome is one of the main points of centrosomal hypothesis of cell aging and differentiation.
K Chichinadze, D Tkemaladze, A Lazarashvili. New class of RNA and centrosomal hypothesis of cell aging]. Advances in gerontology = Uspekhi gerontologii / Rossiĭskai͡a akademii͡a nauk, Gerontologicheskoe obshchestvo. 2012;25(1):23-8
PMID: 22708440
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