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Tandem ring-opening decarboxylation of cyclopropane hemimalonates with sodium azide: a short route to γ-aminobutyric acid esters.
Michael R Emmett, Huck K Grover, Michael A Kerr
Department of Chemistry, Western University, London, Ontario, Canada N6A 5B7.
The Journal of organic chemistry 2012 Aug 3Sizes of these terms reflect their relevance to your search.
Cyclopropane hemimalonates, when treated with sodium azide, undergo a tandem ring-opening decarboxylation to produce γ-azidobutyric acids in good yields. These adducts were hydrogenated to form γ-aminobutyric acid (GABA) methyl esters.
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Michael R Emmett, Huck K Grover, Michael A Kerr. Tandem ring-opening decarboxylation of cyclopropane hemimalonates with sodium azide: a short route to γ-aminobutyric acid esters. The Journal of organic chemistry. 2012 Aug 3;77(15):6634-7
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PMID: 22775774
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