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We herein report the clinical profile of five eyes of three patients with normotensive pseudoexfoliation glaucoma. Three patients who presented with clinical evidence of pseudoexfoliation with evident glaucomatous damage and normal intraocular pressure underwent comprehensive ophthalmic evaluation, central corneal thickness, diurnal IOP recording (in two patients), and visual field examination. Five eyes of the three patients were found to have advanced glaucomatous damage, thin cornea, and an IOP recording of <23 mm Hg at all occasions. Case 1 had macular branch retinal vein occlusion while case 3 had disc collaterals. Normotensive pseudoexfoliation glaucoma may represent a new phenotype highlighting the possible role of pressure-independent mechanisms of glaucoma in pseudoexfoliation.


Aparna Rao. Normotensive pseudoexfoliation glaucoma: a new phenotype? Seminars in ophthalmology. 2012 May-Jul;27(3-4):48-51

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PMID: 22784263

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