Substantial depletion of Langerhans cells leads to their replenishment by bone marrow–derived precursors that access the epidermis through hair follicles, a site of crucial chemokine production.
William R Heath, Scott N Mueller. Hair follicles: gatekeepers to the epidermis. Nature immunology. 2012 Jul 19;13(8):715-7
PMID: 22814342
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