To investigate the value of stimulated intrauterine insemination (IUI) in women with unilateral tubal occlusion. Superovulation and IUI was performed during 2003-2010 and the medical records were reviewed retrospectively. Thirty-seven infertile women (52 cycles) with unilateral tubal occlusion diagnosed by hysterosalpingography and without other causes of infertility were selected. One-hundred fourteen patients with unexplained infertility served as a control group (182 cycles). The main outcome was the clinical pregnancy rate per cycle. The pregnancy rate per cycle was similar, 17.3% for the unilateral tubal occlusion group and 16.5% for the unexplained infertility group. The rate of miscarriage (11.1% vs. 23.3%) and ectopic pregnancy (11.1% vs. 6.7%) was similar between the two groups. The pregnancy rate was higher in patients with proximal occlusion (25.0%) compared with distal occlusion (13.9%) or unexplained infertility, but not statistically significant. Stimulated IUI can be suggested as the initial treatment option in women with unilateral proximal or distal tubal occlusion.
Gwang Yi, Byung Chul Jee, Chang Suk Suh, Seok Hyun Kim. Stimulated intrauterine insemination in women with unilateral tubal occlusion. Clinical and experimental reproductive medicine. 2012 Jun;39(2):68-72
PMID: 22816072
View Full Text