Syndrome of inappropriate secretion of antidiuretic hormone due to desvenlafaxine.

Hyponatremia secondary to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is not uncommon in patients receiving treatment of selective serotonin reuptake inhibitors or venlafaxine. This is a case report of a 47-year-old man with depression, who developed hyponatremia after commencing treatment with desvenlafaxine. To our knowledge, this is the first case in which desvenlafaxine-associated SIADH was reported since the introduction of the drug. Physicians should be aware of the possibility of desvenlafaxine-associated hyponatremia in patients under age of 65. Copyright © 2013 Elsevier Inc. All rights reserved.

Citation

Gary Tin-Ho Lee, Jess Lam-Ming Leung. Syndrome of inappropriate secretion of antidiuretic hormone due to desvenlafaxine. General hospital psychiatry. 2013 Sep-Oct;35(5):574.e1-3

PMID: 22818163

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