Tools for cellular immunology and vaccine research the in the guinea pig: monoclonal antibodies to cell surface antigens and cell lines.

Hubert Schäfer, Reinhard Burger

Robert Koch-Institute Berlin, Nordufer 20, 13353 Berlin, Germany. Schaeferh@rki.de

Vaccine 2012 Aug 31

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The use of monoclonal antibodies directed against membrane proteins of leukocytes has greatly contributed to our understanding of the function and development of the immune system. Meanwhile these reagents provide valuable tools in many fields of research, stretching far beyond immunology and hematology. For guinea pigs only a limited number of such reagents have been described, and the information about availability and specificity is scattered over many years and journals. We provide an overview on the monoclonal antibodies produced since the technique was applied first in this species, with a focus on those reagents which have been characterized in more detail, and which should still be available either commercially or directly from the labs that created them. Copyright © 2012 Elsevier Ltd. All rights reserved.

Citation

Hubert Schäfer, Reinhard Burger. Tools for cellular immunology and vaccine research the in the guinea pig: monoclonal antibodies to cell surface antigens and cell lines. Vaccine. 2012 Aug 31;30(40):5804-11