A Zn2+ specific triazole based calix[4]arene conjugate (L) as a fluorescence sensor for histidine and cysteine in HEPES buffer milieu.

Rakesh Kumar Pathak, Khatija Tabbasum, Ankit Rai, Dulal Panda, Chebrolu Pulla Rao

Bioinorganic Laboratory, Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai 400 076, India.

The Analyst 2012 Sep 7

filter terms:

A highly fluorescent Zn(2+) complex of the triazole linked salicyl-imino-thiophenyl conjugate of calix[4]arene, [ZnL] has been demonstrated to be a chemo-sensing ensemble for the recognition of His and Cys among the naturally occurring amino acids in HEPES buffer milieu. The recognition behaviour of the [ZnL] towards these amino acids has been shown on the basis of fluorescence, absorption and visual fluorescent colour changes. The species of recognition were shown by ESI MS titrations, AFM & TEM microscopy and cell studies.

Citation

Rakesh Kumar Pathak, Khatija Tabbasum, Ankit Rai, Dulal Panda, Chebrolu Pulla Rao. A Zn2+ specific triazole based calix[4]arene conjugate (L) as a fluorescence sensor for histidine and cysteine in HEPES buffer milieu. The Analyst. 2012 Sep 7;137(17):4069-75