Desferrioxamine-related ocular toxicity: a case report.

Sumu Simon, Paul A Athanasiov, Rajeev Jain, Grant Raymond, Jagjit S Gilhotra

Indian journal of ophthalmology 2012 Jul

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A 29-year-old lady receiving repeated blood transfusions for β thalassemia since childhood, presented with rapidly deteriorating symptoms of night blindness and peripheral visual field loss. She was recently commenced on high-dose intravenous desferrioxamine for reducing the systemic iron overload. Clinical and investigative findings were consistent with desferrioxamine-related pigmentary retinopathy and optic neuropathy. Recovery was partial following cessation of desferrioxamine. This report highlights the ocular side-effects of desferrioxamine mesylate and the need to be vigilant in patients on high doses of desferrioxamine.

Citation

Sumu Simon, Paul A Athanasiov, Rajeev Jain, Grant Raymond, Jagjit S Gilhotra. Desferrioxamine-related ocular toxicity: a case report. Indian journal of ophthalmology. 2012 Jul;60(4):315-7