Expeditious synthesis of saponin P57, an appetite suppressant from Hoodia plants.

Jian Zhang, Hefang Shi, Yuyong Ma, Biao Yu

State Key Laboratory of Bio-organic & Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.

Chemical communications (Cambridge, England) 2012 Sep 7

filter terms:

Pregnane glycoside P57, the appetite suppressant component from Hoodia, was synthesized expeditiously, featuring preparation of the aglycone Hoodigogenin A from digoxin and assembly of the deoxytrisaccharide with glycosyl o-alkynylbenzoates as donors.

Citation

Jian Zhang, Hefang Shi, Yuyong Ma, Biao Yu. Expeditious synthesis of saponin P57, an appetite suppressant from Hoodia plants. Chemical communications (Cambridge, England). 2012 Sep 7;48(69):8679-81