Correlation Engine 2.0
Clear Search sequence regions

filter terms:
  • acetate (1)
  • anion binding (2)
  • anions (2)
  • azides (1)
  • bromide (1)
  • iodide (1)
  • Sizes of these terms reflect their relevance to your search.

    Three tetra-triazole macrocycles were synthesized in good yields by the copper(i)-catalysed cycloaddition of bis-triazole azides and bis-alkynes. One of these was alkylated to give a cyclic tetra-triazolium receptor, which complexes anions strongly in competitive DMSO-water mixtures. In 1 : 1 DMSO-water, the tetracationic receptor exhibits a preference for the larger halides, bromide and iodide, with all halides associating more strongly than the oxoanion, acetate. The sulfate dianion is complexed far more strongly than any of the monobasic anions (K(a) > 10(4) M(-1)). Quantum mechanics/molecular mechanics simulations corroborate the experimentally determined anion binding selectivity trends.


    Nicholas G White, Sílvia Carvalho, Vítor Félix, Paul D Beer. Anion binding in aqueous media by a tetra-triazolium macrocycle. Organic & biomolecular chemistry. 2012 Sep 14;10(34):6951-9

    PMID: 22829100

    View Full Text