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Direct glycosylation of sugar oximes and HONHFmoc has been realized for the first time by using glycosyl ortho-hexynylbenzoates as donors under the catalysis of PPh(3)AuOTf, providing an effective approach to the synthesis of N-O linked saccharides, which are of great biological interest.

Citation

Jun Yu, Jiansong Sun, Biao Yu. Construction of interglycosidic N-O linkage via direct glycosylation of sugar oximes. Organic letters. 2012 Aug 3;14(15):4022-5

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PMID: 22831485

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