High-density lipoproteins as a form of daunorubicin transport in hepatoma cells of mice].

The efficiency of using high-density lipoproteins (HDLPs) as the transport form of an antineoplastic drug daunorubicin (rubomycin hydrochloride, daunoxome) has been shown on the culture of HA-1 hepatoma cells of mice. The use of HDLPs in a complex with daunorubicin led to an increase in the efficiency of drug transport and cytotoxic action with respect to tumor cells in comparison with hepatocytes of healthy animals.

Citation

D V Sumenkova, L M Poliakov, L E Panin. High-density lipoproteins as a form of daunorubicin transport in hepatoma cells of mice]. Eksperimental'naia i klinicheskaia farmakologiia. 2012;75(5):32-4

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PMID: 22834127

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