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Short synthesis of diamide-linked sucrose macrocycles.
Mykhaylo A Potopnyk, Piotr Cmoch, Sławomir Jarosz
Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.
Organic letters 2012 Aug 17Sizes of these terms reflect their relevance to your search.
A convenient route to macrocyclic diamide-linked macrocyclic derivatives with a sucrose scaffold is presented. Reaction of sucrose based amines (o- and m-) with acid dichlorides afforded the monomeric macrocycles in excellent yields, while reaction of the p-amines also provided dimeric products.
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Mykhaylo A Potopnyk, Piotr Cmoch, Sławomir Jarosz. Short synthesis of diamide-linked sucrose macrocycles. Organic letters. 2012 Aug 17;14(16):4258-61
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PMID: 22853688
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