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    Decision making is often considered to arise out of contributions from a model-free habitual system and a model-based goal-directed system. Here, we investigated the effect of a dopamine manipulation on the degree to which either system contributes to instrumental behavior in a two-stage Markov decision task, which has been shown to discriminate model-free from model-based control. We found increased dopamine levels promote model-based over model-free choice. Copyright © 2012 Elsevier Inc. All rights reserved.


    Klaus Wunderlich, Peter Smittenaar, Raymond J Dolan. Dopamine enhances model-based over model-free choice behavior. Neuron. 2012 Aug 09;75(3):418-24

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    PMID: 22884326

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