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The diversity of tet(S) genetic contexts of 13 enterococci from human, animal, and environmental samples from different geographical areas is reported. The tet(S) gene was linked to either CTn6000 variants of chromosomal location or composite platforms flanked by IS1216 located on plasmids (∼40 to 115 kb). The comparative analysis of all tet(S) genetic elements available in the GenBank databases suggests that CTn6000 might be the origin of a variety of tet(S)-carrying platforms that were mobilized to different plasmids.

Citation

Carla Novais, Ana R Freitas, Eduarda Silveira, Fernando Baquero, Luísa Peixe, Adam P Roberts, Teresa M Coque. Different genetic supports for the tet(S) gene in Enterococci. Antimicrobial agents and chemotherapy. 2012 Nov;56(11):6014-8

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PMID: 22908170

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