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In selected stroke patients intravenous thrombolysis and/or endovascular therapies lead to a significant reduction of long term disabilities. In case of no contraindications, patients with acute ischemic stroke, which arrive within the time window on the emergency unit, should receive thrombolysis consequently and current data indicate that patients with a severe acute ischemic stroke and a proximal cerebral arterial vessel occlusion (i. e. main stem of the arteria cerebri media, posterior, maybe also anterior, arteria carotis interna and basilaris) should preferentially be treated endovascularly, patients with a peripheral cerebral arterial vessel occlusion (i. e. main branch of the arteria cerebri media, anterior and posterior) and mild symptoms with intravenous thrombolysis.


M Heldner, J Gralla, H Hungerbühler, U Fischer, M Arnold. Acute occlusions of cerebral arterial vessels - intravenous versus intraarterial thrombolysis]. Therapeutische Umschau. Revue thérapeutique. 2012 Sep;69(9):511-6

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PMID: 22923354

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