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This report describes our experience concerning gastrointestinal perforation due to necrotizing enterocolitis during a 10-year period. The cases of 27 gastrointestinal perforations, which were treated in our hospital, were retrospectively reviewed. All patients were neonates and infants up to the age of 2 months. The study population consisted of 16 boys (59.3%) and 11 girls (40.7%). Twenty-one neonates (77.8%) were preterm, and the median gestational age was 28 weeks. Twenty-four cases (88.9%) of perforation underwent laparotomy. The overall mortality was 63%. Seventy-six percent of the preterm neonates and only 16.7% of the full-term neonates died. Gastrointestinal perforation is still connected with a high mortality rate, with necrotizing enterocolitis being the main cause of death. The neonates who did not undergo surgery all died.

Citation

George Sakellaris, Nikolaos Partalis, Olga Dede, Athanasios Alegakis, Chrisa Seremeti, Eftichia Korakaki, Christina Giannakopoulou. Gastrointestinal perforations in neonatal period: experience over 10 years. Pediatric emergency care. 2012 Sep;28(9):886-8

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PMID: 22929145

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