Molecular AND logic gate based on bacterial anaerobic respiration.

Mary Anitha Arugula, Namita Shroff, Evgeny Katz, Zhen He

Department of Civil Engineering and Mechanics, University of Wisconsin-Milwaukee, Milwaukee, WI 53211, USA.

Chemical communications (Cambridge, England) 2012 Oct 21

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Enzyme coding genes that integrate information for anaerobic respiration in Shewanella oneidensis MR-1 were used as input for constructing an AND logic gate. The absence of one or both genes inhibited electrochemically-controlled anaerobic respiration, while wild type bacteria were capable of accepting electrons from an electrode for DMSO reduction.

Citation

Mary Anitha Arugula, Namita Shroff, Evgeny Katz, Zhen He. Molecular AND logic gate based on bacterial anaerobic respiration. Chemical communications (Cambridge, England). 2012 Oct 21;48(82):10174-6