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To determine the relationship between the change in middle cerebral artery peak systolic velocity (MCA-PSV) and the change in fetal Hemoglobin (Hb) immediately following intrauterine transfusion (IUT). Study data included all IUTs performed for suspected fetal anemia from 2007-2011. Sixty-eight IUTs were performed for 23 pregnancies, demonstrating a statistically significant MCA-PSV decrease for up to four IUTs. Significant correlations between changes in Hb levels and MCA-PSV were not detected. MCA-PSV values were highly variable in the immediate post-operative period and did not correlate with the Hb change.


Brendan H Grubbs, Lisa M Korst, Arlyn Llanes, Ramen H Chmait. Middle cerebral artery Doppler and hemoglobin changes immediately following fetal transfusion. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2013 Jan;26(2):155-7

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PMID: 22937816

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