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Epinephrine is crucial in the treatment of anaphylaxis. As anaphylaxis frequently occurs in nonmedical settings, use of an epinephrine auto-injector is vital for prompt management. This article provides an overview of the increasing number of epinephrine auto-injector prescriptions and the underlying causes and contributing factors to these rising prescriptions. It also reviews the current indications for prescription of an epinephrine auto-injector, proper use of epinephrine auto-injectors, and the management of unintentional epinephrine injections.


Ronna L Campbell, Veena Manivannan, Martha F Hartz, Annie T Sadosty. Epinephrine auto-injector pandemic. Pediatric emergency care. 2012 Sep;28(9):938-42

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PMID: 22940899

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