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Fluorescence quenching of gold nanoparticles integrating with a conformation-switched hairpin oligonucleotide probe for microRNA detection.

Yunqiu Tu, Ping Wu, Hui Zhang, Chenxin Cai

Jiangsu Key Laboratory of New Power Batteries, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, PR China.

Chemical communications (Cambridge, England) 2012 Nov 11


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    We report a new strategy for microRNA analysis based on the fluorescence quenching of gold nanoparticles (AuNPs) integrating with a conformation-switched hairpin-structured oligonucleotide probe for improving selectivity.

    Citation

    Yunqiu Tu, Ping Wu, Hui Zhang, Chenxin Cai. Fluorescence quenching of gold nanoparticles integrating with a conformation-switched hairpin oligonucleotide probe for microRNA detection. Chemical communications (Cambridge, England). 2012 Nov 11;48(87):10718-20

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    PMID: 22945460

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