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We report a new strategy for microRNA analysis based on the fluorescence quenching of gold nanoparticles (AuNPs) integrating with a conformation-switched hairpin-structured oligonucleotide probe for improving selectivity.

Citation

Yunqiu Tu, Ping Wu, Hui Zhang, Chenxin Cai. Fluorescence quenching of gold nanoparticles integrating with a conformation-switched hairpin oligonucleotide probe for microRNA detection. Chemical communications (Cambridge, England). 2012 Nov 11;48(87):10718-20

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PMID: 22945460

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