Early duodenal adenocarcinoma resembling a submucosal tumor cured with endoscopic resection: a case report.

Primary adenocarcinomas resembling submucosal tumors are rare in the gastrointestinal tract. Almost all the submucosal tumor-like adenocarcinomas previously reported invaded the submucosa or deeper. Therefore, submucosal tumor-like lesions are usually treated by surgical resection, and those that arise in the duodenum have been treated by pancreaticoduodenectomy. A 65-year-old Japanese man was diagnosed with a submucosal tumor-like adenocarcinoma in his duodenum. We considered it possible that the tumor invasion was limited to the mucosal or submucosal layers and could be removed by endoscopic resection. Tumor histopathology revealed a well-differentiated adenocarcinoma confined to the muscularis mucosae with no lymphovascular invasion. Complete resection of the carcinoma was achieved and there has been no recurrence three years after endoscopic resection. We suggest that submucosal tumor-like adenocarcinomas arising in nonampullary duodenal sites should be diagnosed carefully with a view to possible endoscopic resection.

Citation

Akira Dobashi, Kenichi Goda, Noboru Yoshimura, Kazuki Sumiyama, Hirobumi Toyoizumi, Shoichi Saito, Tomohiro Kato, Hiroki Ishikawa, Katsuhiko Yanaga, Hisao Tajiri, Masahiro Ikegami. Early duodenal adenocarcinoma resembling a submucosal tumor cured with endoscopic resection: a case report. Journal of medical case reports. 2012 Sep 04;6:280

PMID: 22947132

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