Urine metabolomics.
Aihua Zhang, Hui Sun, Xiuhong Wu, Xijun Wang
National TCM Key Lab of Serum Pharmacochemistry, Heilongjiang University of Chinese Medicine, and Key Pharmacometabolomics Platform of Chinese Medicines, Heping Road 24, Harbin 150040, China.
Clinica chimica acta; international journal of clinical chemistry 2012 Dec 24Metabolomics is a powerful technique for the discovery of novel biomarkers and elucidation of biochemical pathways to improve diagnosis, prognosis and therapy. An advantage of this approach is its ability to assess global metabolic profiles to enhance pathologic characterization. Urine is an ideal bio-medium for disease study because it is readily available, easily obtained and less complex than other body fluids. Ease of collection allows for serial sampling to monitor disease and therapeutic response. Because of this potential, this paper will review urine metabolomic analysis, discuss its significance in the post-genomic era and highlight the specific roles of endogenous small molecule metabolites in this emerging field. Copyright © 2012 Elsevier B.V. All rights reserved.
Citation
Aihua Zhang, Hui Sun, Xiuhong Wu, Xijun Wang. Urine metabolomics. Clinica chimica acta; international journal of clinical chemistry. 2012 Dec 24;414:65-9
Mesh Tags
Substances
PMID: 22971357
View Full Text
