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Assessment of in vitro skin irritation potential of nanoparticles: RHE model.

P Balakrishna Murthy, A Sairam Kishore, P Surekha

International Institute for Biotechnology and Toxicology (IIBAT), Kancheepuram, Tamil Nadu, India. director@iibat.com

Methods in molecular biology (Clifton, N.J.) 2012


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    The skin irritation test is designed for the prediction of acute skin irritation of nanoparticles by measurement of its cytotoxic effect, as reflected in the MTT assay, on the Reconstructed Human Epidermis (RHE) model. RHE tissues are commercially available.

    Citation

    P Balakrishna Murthy, A Sairam Kishore, P Surekha. Assessment of in vitro skin irritation potential of nanoparticles: RHE model. Methods in molecular biology (Clifton, N.J.). 2012;926:219-34

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    PMID: 22975968

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