CSF kynurenic acid and suicide risk in schizophrenia spectrum psychosis.

Andreas Carlborg, Jussi Jokinen, Erik G Jönsson, Sophie Erhardt, Peter Nordström

Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University Hospital Solna, SE-171 76 Stockholm, Sweden. andreas.carlborg@sll.se

Psychiatry research 2013 Jan 30

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Relationships between concentrations of cerebrospinal fluid (CSF) kynurenic acid (KYNA) and suicidal behavior were evaluated in 59 patients with psychosis after 22 years of follow-up. Three patients died from suicide and nine patients had a history of attempted suicide. Patients with attempted suicide had significantly lower concentrations of CSF KYNA. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Citation

Andreas Carlborg, Jussi Jokinen, Erik G Jönsson, Sophie Erhardt, Peter Nordström. CSF kynurenic acid and suicide risk in schizophrenia spectrum psychosis. Psychiatry research. 2013 Jan 30;205(1-2):165-7