The role of mass spectrometry in the analysis of vitamin D compounds.

Rose M Gathungu, Caroline C Flarakos, G Satyanarayana Reddy, Paul Vouros

Barnett Institute of Chemical and Biological Analysis, Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, USA.

Mass spectrometry reviews 2013 Jan-Feb

filter terms:

This review highlights the superseding role of mass spectrometry in the structural characterization and quantitation of vitamin D compounds in comparison to other analytical methods (e.g., UV, bioassays) that lack the sensitivity and specificity of mass spectrometry. After a short introduction to the biochemistry of vitamin D compounds, an overview of the current techniques to characterize and quantitate vitamin D compounds is given with emphasis on the contribution of mass spectrometry. Copyright © 2012 Wiley Periodicals, Inc.

Citation

Rose M Gathungu, Caroline C Flarakos, G Satyanarayana Reddy, Paul Vouros. The role of mass spectrometry in the analysis of vitamin D compounds. Mass spectrometry reviews. 2013 Jan-Feb;32(1):72-86