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Remote heating of gold nanoparticles (GNPs) by low frequency electromagnetic field has been recently proposed as a potential thermal treatment for deep-seated tumors - almost all the studies were conducted on a commercial device at 13.56 MHz. This work investigates the electromagnetic heating of GNP dispersions at 200 kHz. GNPs are synthesized based on an improved citrate reduction method, and the influence of particle concentration and impurity on the bulk heating effect at 200 kHz are investigated. The results demonstrate that GNPs alone can contribute to an appreciable bulk temperature increase, which increases with GNP concentration in a nonlinear fashion. For a nonmagnetic material, the specific absorption rate of GNPs can reach that of Fe(3)O(4) nanoparticle dispersions. Such a result cannot be explained by either the Joule heating or hysteresis heating mechanism.


Hui-Jiuan Chen, Dongsheng Wen. Experimental study of electromagnetic heating of gold nanoparticle dispersions at 200 kHz. Nanomedicine (London, England). 2013 Feb;8(2):215-22

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PMID: 22998408

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