Correlation Engine 2.0
Clear Search sequence regions


The highly polymorphic Human Leukocyte Antigen system encompasses different loci that have been studied in transplantation as well as diseases and population associated research. This study is the first and largest of its kind to describe the distribution of HLA-A, -B and -C alleles in Lebanon. Respectively, 1994, 1309 and 1163 Lebanese individuals referred for HLA typing and possible bone marrow/kidney donation were tested for HLA-A, HLA-B and HLA-C alleles using the polymerase chain reaction/Sequence specific priming (PCR-SSP) method. Our data were compared to that of several populations with interesting and common findings shared with the Moroccan, Jordanian, Tunisian, Omani, Korean, Chinese, Japanese, Peruan, Bulgarian, Irish, Polish, Spanish, Swiss, American, African and Brazilian populations. The following data concerning the Lebanese population will help future investigators to study the relation of HLA-A, -B and -C alleles with common diseases in Lebanon and will add to the available international literature. This new data will serve as a major reference report in the region. Copyright © 2012 Elsevier B.V. All rights reserved.

Citation

Sara Khansa, Rouba Hoteit, Dina Shammaa, Rabab Abdel Khalek, Hussein El Halas, Layal Greige, Fatmeh Abbas, Rami A R Mahfouz. HLA class I allele frequencies in the Lebanese population. Gene. 2013 Jan 10;512(2):560-5

Expand section icon Mesh Tags

Expand section icon Substances


PMID: 23000566

View Full Text