Bookmark
Forward
An engineered lantipeptide synthetase serves as a general leader peptide-dependent kinase.
Chemical communications (Cambridge, England) 2012 Nov 07Sizes of these terms reflect their relevance to your search.
Phosphorylation is an abundant post-translational modification involved in a myriad of cell signaling pathways. Herein, we have engineered the class II lantipeptide synthetase ProcM to generate a variety of peptides containing O-phosphoserine (pSer) and O-phosphothreonine (pThr) residues, either in vitro or in vivo.
Citation
Gabrielle N Thibodeaux, Wilfred A van der Donk. An engineered lantipeptide synthetase serves as a general leader peptide-dependent kinase. Chemical communications (Cambridge, England). 2012 Nov 07;48(86):10615-7
Mesh Tags
Substances
PMID: 23001385
View Full Text
