Effect of niclosamide spreading oil on killing schistosome cercariae].

Dechlorinated water (100 ml, 30 degrees C) was put into a plate (diameter 15 cm), and 1% niclosamide spreading oil 5 microl was added, then a ring of Schistosoma japonicum cercariae were picked up to the plate. The time of killing all the cercariae was observed at three time points (immediately, 24, 48 h), and the dechlorinated water was used as control. The results showed that schistosome cercariae were all killed in three minutes by 1% niclosamide spreading oil at the three time points. The cercaria-killing effects of each time point were not significantly different (F = 0.062, P > 0.05). The cercariae were alive in the control in 48 h.

Citation

Guo-Hua Peng, Zhu-Hua Hu, Zi-Ping Bao, Yi-Sheng Zhou, Zhi-Wei Xiong, Hai-Ying' Chen, Jia-Gang Guo. Effect of niclosamide spreading oil on killing schistosome cercariae]. Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control. 2012 Jun;24(3):368, 370

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PMID: 23012973

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