Intestinal amyloidosis with intractable diarrhea and intestinal pseudo-obstruction.

Yeon-Joo Kim, Hyun-Soo Kim, Seon-Young Park, Sang-Woo Park, Yoo-Duk Choi, Chang-Hwan Park, Sung-Kyu Choi, Jong-Sun Rew

Departments of Internal Medicine and Pathology, Chonnam National University Medical School, Gwangju, Korea.

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 2012 Sep 25

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We report herein a case of intestinal amyloidosis with grave prognosis that caused intractable diarrhea and intestinal pseudo-obstruction, alternately in spite of intensive conservative treatment. A 44-year-old woman was admitted for fever, diarrhea, and crampy abdominal pain which had been continuned during 6 months. Abdomen CT scan showed edematous wall thickening of the small bowel and right colon, and colonoscopic biopsy revealed amyloid deposition in the mucosa. Monoclonal light chains in serum and/or urine were not detected and highly elevated serum amyloid A was shown. In spite of intensive treatment including oral prednisolone and colchicine, diarrhea and intestinal pseudo-obstruction developed alternately, general status rapidly got worsened and died after two months.

Citation

Yeon-Joo Kim, Hyun-Soo Kim, Seon-Young Park, Sang-Woo Park, Yoo-Duk Choi, Chang-Hwan Park, Sung-Kyu Choi, Jong-Sun Rew. Intestinal amyloidosis with intractable diarrhea and intestinal pseudo-obstruction. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi. 2012 Sep 25;60(3):172-6